Diabetes Cure Guide

Diabetes research done in the Peninsula Medical School shows that genes play a big role in the development of Type 2 diabetes, and thus they were able to study the predictability on the onset of the disease. Also, scientists in this study are optimistic that coming up with a more accurate prediction is a good way to prevent the disease or at least reduce its effects.

The study tried to go beyond the accepted hypothesis that diabetes symptoms are linked to overweight people and appear on those who are beyond 40 years old. The team theorized that there could be some other cause of the disease especially since in recent years more and more children have been diagnosed with the condition. Thus, the study was commenced holding in mind the possibility of using one’s genetic make-up to predict the probability of the diabetes being acquired by that person.

The team looked for variants within the human genome that related the risk of Type 2 diabetes by the process of examining thousands of DNA samples from across the UK.

They likened the process to identifying the types of DNA that result in the three main eye-color types. The team compared the genes together and they were able to take the first step in coming up with a predictive value through genetics so Type 2 diabetes can be prevented and controlled.

Results of the study show that approximately four percent of the population is at much higher risk than other group of people. Such outcome is believed to better mainstream the prediction for Type 2 diabetes in a given population. Another result of the study suggested that Type 2 diabetes is best treated with lifestyle changes such as healthier diet, weight loss, and increased physical activity. They also added that insulin may be a good help to achieve normal blood glucose levels.

Another diabetes research study conducted in the University of Calgary is believed as another breakthrough as the research team found that a protein in the pancreas called glutamic acid decarboxylase or GAD do play a critical role in the initiation of autoimmune Type 1 diabetes in mice. The team demonstrated that GAD suppression can be prevented by the immune system’s destruction of the insulin-producing cells. Thus, they were safe to conclude that immunizing animals prone to diabetes at an early age can prevent the onset of the disease in adulthood.

Their findings are believed to have important therapeutic implications for the treatment of autoimmune Type 1 diabetes in people. This discovery may lead to a method of increasing the survival of transplanted insulin-producing pancreatic islet tissue and a method of preventing diabetes in individuals at high risk.

The team further studied whether GAD-suppressed pancreatic tissue would survive when transplanted into diabetic mice. One proposed cure for diabetes is the transplantation of healthy, insulin-producing pancreatic tissue into diabetic patients. Researchers’ past attempts to do this have failed. This study shows that when diabetic mice are given transplants of GAD-suppressed pancreatic tissue, the mice have no recurrence of diabetes without destruction of the transplanted tissue.

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